Major guideline recommendations for secondary stroke2-4
European Stroke Organisation (ESO), World Stroke Organization (WSO), and American Heart Association (AHA)/American Stroke Association (ASA) guidelines provide comprehensive recommendations to reduce the risk of recurrent ischemic stroke in people who have suffered a stroke or TIA.2-4
Management of noncardioembolic ischemic stroke or high-risk TIA for secondary stroke prevention2-4
Dual antiplatelet therapy (DAPT) followed by single antiplatelet therapy (SAPT) is often used, with DAPT use dependent upon the timing and severity of the index ischemic event.2-5
In patients who have suffered an acute minor noncardioembolic ischemic stroke or TIA in the previous 24 hours, treatment guidelines generally recommend DAPT with acetylsalicylic acid (ASA) and ticagrelor/clopidogrel for up to 90 days, followed by SAPT.2-5
Please see guidelines for complete details on these recommendations.
Treatment and lifestyle changes are essential for secondary stroke prevention2-4
Statins are the first-line treatment for lowering low-density lipoprotein cholesterol (LDL-C) in patients who have had a stroke or TIA.2-4
Antihypertensive therapy is recommended for all patients with hypertension and a history of stroke or TIA.2-4
Lifestyle changes, including dietary changes, physical activity, and smoking and substance abuse cessation, are also recommended.2-4
~1 in 10 ischemic stroke survivors
will have another stroke within 1 year6,7
Secondary stroke deserves another look
- Kolmos M, et al. J Stroke Cerebrovasc Dis. 2021;30(8):105935.
- Kleindorfer DO, et al. Stroke. 2021;52(7):e364–e467.
- Dawson J, et al. Eur Stroke J. 2022;7:I–XLI.
- Mead GE, et al. Int J Stroke. 2023;18(5):499–531.
- Dawson J, et al. Eur Stroke J. 2021;6(2):CLXXXVII–CXCI.
- Kolmos M, et al. J Stroke Cerebrovasc Dis. 2021;30(8):105935.
- Wang Y, et al. PLoS ONE. 2023;18(8):e0289790.
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